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Ética erótica: Una manera diferente de sentir by Javier Sádaba

By Javier Sádaba

Para l. a. mayoría, los angeles ética no es más que una mera exposición y discusión de los deberes positivos y negativos que tendrían que regir el comportamiento humano. Pero esa concepción de los angeles ética queda coja. Le falta el desarrollo de l. a. vida buena y l. a. felicidad, dos aspectos sumamente importantes y a los que no se les presta los angeles necesaria atención.

A esa otra ética, l. a. ética erótica, que no habla de obligaciones, sino que aconseja y recuerda, que abarca todo tipo de ámbitos y contextos, tanto de l. a. vida pública como de los angeles privada, dedica Javier Sádaba este libro.Porque esa es l. a. ética que atiende a nuestros deseos teniendo siempre presente, frente al realismo chato, que somos un haz de posibilidades.

Con humor, con sensibilidad y con elegancia, el autor de los angeles vida buena defiende en esta obra los angeles imaginación, los distintos placeres y el respeto a las diferentes formas de sentir, y reivindica, de forma apasionada, una ética que dé l. a. palabra a los sentidos, a los sentimientos y, de manera muy especial, a los deseos.

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Ética erótica: Una manera diferente de sentir

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Vilain: I know of two human sex-reversal cases with duplications of relatively large chromosomal regions. One is a duplication of 22q that leads to XX sex reversal (one case of XX hermaphrodite and one case of XX male). In the other, there is duplication of 17p leading to an XX male. What is interesting about these two cases is that these regions both contain SOX genes: 22q has SOX10 and 17p has SOX20. One could argue that any region that is duplicated in humans that contains a SOX gene that happens to be expressed in the gonad may be able to replace SRY just by dosage e¡ects.

At present we do not know whether +KTS variants are involved in transcriptional activation of the Sry gene or whether they may act through a di¡erent mechanism. Given the evidence from in vivo studies, which indicate a role for +KTS in RNA binding (Kennedy et al 1996, Caricasole et al 1996), it is tempting to speculate that it may be involved in stabilising the Sry mRNA by binding to it. Future experiments will be aimed to address this question. Sox9 is su⁄cient to induce testis formation in XX mice We have seen that WT1+KTS is required for the expression of high levels of the sex determining gene Sry.

For all we know, the RNA is localized through the 3’ UTR, and where it is localized it is translated. Perhaps this creates a localized high concentration. I’m just suggesting that there could be many elements of regulation here that we are not in touch with. Swain: And WT1 might be involved in this process. Goodfellow: Has any more work been done in those species where there has been Sry ampli¢cation, looking for potentially co-ampli¢ed genes? The rat has 20 copies of Sry, although it is not clear how many of these are active.

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